tag:blogger.com,1999:blog-7049415900026167371.post7664308383383759794..comments2024-03-09T09:22:49.890+02:00Comments on Inhuman Experiment: My Current Health Regimen v2.0JLLhttp://www.blogger.com/profile/01200324973565346888noreply@blogger.comBlogger57125tag:blogger.com,1999:blog-7049415900026167371.post-38328773783851566102012-03-10T19:48:21.518+02:002012-03-10T19:48:21.518+02:00My bad, I had proteins in mind when I said pre and...My bad, I had proteins in mind when I said pre and post-workout. I agree about carbs being useful only post-workout for muscle growth.Florent Berthethttps://www.blogger.com/profile/05754663217643339589noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-78975915891950002672012-03-10T18:07:57.422+02:002012-03-10T18:07:57.422+02:00@Florent Berthet,
I think it's been shown tha...@Florent Berthet,<br /><br />I think it's been shown that carbs pre-workout *don't* help muscle growth. For post-workout, I think rice and potatoes are both okay.<br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-4000115590161237432012-02-07T20:20:11.865+02:002012-02-07T20:20:11.865+02:00It's been shown that carbs pre and post-workou...It's been shown that carbs pre and post-workout are useful for muscle growth. What would be your advice in that regard? Is rice ok in this case (since blood glucose will probably be used by muscles, maybe less glycation will occur?). <br /><br />Or would you prefer potatoes or other sources of carbs?Florent Berthethttps://www.blogger.com/profile/05754663217643339589noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-57275725485669672262011-10-31T21:31:38.592+02:002011-10-31T21:31:38.592+02:00@Anonymous,
I've avoided rice because of its ...@Anonymous,<br /><br />I've avoided rice because of its high glycemic index and because I was on a low-carb diet anyway. I think white rice is relatively neutral -- calorie for calorie, it's definitely not the best source of nutrients, but it doesn't seem to be all that harmful either. I'm not really avoiding rice anymore (nor potatoes for that matter). <br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-46318460042596647832011-10-29T13:57:55.377+03:002011-10-29T13:57:55.377+03:00Why rice?
Just wondering why you are choosing to ...Why rice?<br /><br />Just wondering why you are choosing to avoid rice? Is it because of its high glycemic index? I agree with the other things you are limiting like grains (especially wheat), dairy, fruit juices, etc. Rice seems to be not so bad to me. Its gluten free, good source of protein, fibre & b vitamins in its whole form (brown) and basmati rice has a low-moderate glycemic index, brown basmati is even better, i think somewhere around 40-55. Jasmine rice on the other hand has a GI of 101!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-69988796116358948722011-06-21T10:48:50.270+03:002011-06-21T10:48:50.270+03:00@Braven,
I am not convinced that increasing mTOR ...@Braven,<br /><br />I am not convinced that increasing mTOR is detrimental to longevity, even though reducing it might be positive. Same thing with IGF-1, it looks like it's necessary to reduce IGF-1 if you want to benefit from CR, but I'm unaware of any studies showing that increasing IGF-1 from the baseline would increase mortality (or have a "pro-aging" effect). <br /><br />As for meat/fish vs. whey, my understanding is the source of protein does not matter so much as the quality of the protein -- as in, protein synthesis is the key, not whether the amino acids come from meat or fish or whey.<br /><br />All in all, I don't think there is at the moment a realistic way to combine sports with CR. Increased energy consumption means increased energy/protein intake. However, even though properly done CR is better for longevity than doing nothing, strength training seems better than doing nothing too. <br /><br />The effect of the strictest CR diet in humans would result in maybe 5 extra years, which is not that much in the grand scheme of things, if you're still relatively young. <br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-47319782502811895572011-06-19T11:11:50.584+03:002011-06-19T11:11:50.584+03:00JLL, I think you should take a look to this:
http:...JLL, I think you should take a look to this:<br />http://eatingoffthefoodgrid.blogspot.com/2010/12/neu5gc-live-fast-die-young.html<br /><br />http://www.eurekalert.org/pub_releases/2008-11/uoc--her111308.php<br /><br />http://www.news-medical.net/news/20100726/Neu5Gc-in-drugs-provokes-strong-immune-response.aspx?page=2Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-59484381164046590372011-06-18T00:55:06.083+03:002011-06-18T00:55:06.083+03:00@JLL
Great blog! I will follow a similar approach...@JLL<br /><br />Great blog! I will follow a similar approach, except I need some modifications as my diet is drastically different from this and a little advice. <br /><br />I have been doing an eating condensed window 18/6 for the past 6 months, and actually have had a very high fat and high protein intake. Around 100-120 a day, now I need to cut that. <br /><br />Everything I was doing the past few years was directed to stimulate the mTOR to elicit growth as I weight train and needed it for my sports, however, after reading this blog I am very disappointed to find out the truth to what I have been doing to myself.<br /><br />So if you could answer my question it would be just wonderful. I am still training and wondering if I were cut out any meat/fish/eggs/etc on days I train and have whey if it would have the same effect. <br /><br />Now I no that stimulating the mTOR to the degree I was is the exact opposite of what I want to do, but I still need to stimulate it at least right after an intense workout and let it tapper off until the next workout. <br /><br />I would be able to answer my own question if I had the knowledge on IGF1, but I am not sure.<br /><br /><br />Does this also mean that fasting, since it increases GH, should not be done?<br /><br />As everyone can see I am not to sure about IGF1, and actually anyone advice would be greatly appreciated.Bravenhttps://www.blogger.com/profile/01030827693869954269noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-21852478292114883192011-06-16T00:40:45.034+03:002011-06-16T00:40:45.034+03:00This comment has been removed by the author.Bravenhttps://www.blogger.com/profile/01030827693869954269noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-5566319423202140982011-04-12T21:51:56.672+03:002011-04-12T21:51:56.672+03:00@Anonymous,
Back when I wrote this article, proba...@Anonymous,<br /><br />Back when I wrote this article, probably 3-5 tablespoons per day. I didn't (and don't) exactly drink it out of the bottle, except when I want to taste the oil by itself, I would just pour it on any food basically.<br /><br />I think these days my fat intake is somewhat lower -- at least the 70% estimate seems high. I'm using more vegetables than I used to, even though I'm still lowish on carbs. <br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-81119047625468503532011-04-12T21:23:31.915+03:002011-04-12T21:23:31.915+03:00Hey JLL,
how much olive oil do you cosume a day. ...Hey JLL,<br /><br />how much olive oil do you cosume a day. Do you literally just drink t straight?<br /><br />Thanks.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-50985797944058890762011-03-16T20:19:45.779+02:002011-03-16T20:19:45.779+02:00Haven't been here in a while, but hope you'...Haven't been here in a while, but hope you're doing great!<br /><br />Seems like your naturally going a bit higher carb a la Matt Stone. <br /><br />Someone commented that Matt thinks short term calorie restriction will slow the metabolism. I think that's false especially since Matt is in general in favor of Martin Berkhan's Lean Gains IF methodology.<br /><br />Yes he doesn't cite his sources, but his blog got me off low carb and I've been feeling excellent eating lots of rice and potatoes again. I started to get a gag reflex whenever I eat fried eggs in butter. Now they almost have to be hard or soft boiled.danimalnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-17594069973490169382010-08-12T18:01:13.831+03:002010-08-12T18:01:13.831+03:00@JLL
I put myself in the latter group also.
I a...@JLL<br /><br />I put myself in the latter group also.<br /> <br />I agree that excessive running does not make sense from an anti-aging standpoint due to the problems many long distance runners have with joint wear and other running related injuries that sometimes pull them out of running altogether. A balance of cardio and strength training a few times a week at moderate to intense levels would be ideal. Cardio can come from a variety of sources other than pounding the pavement; biking, swimming, stair climbing, hiking, elliptical, an aerobics class/video, and so on. Regular exercise is the key. Selecting the proper shoe type and surface can also make a difference when running. Run at a track or on a good treadmill rather than on a hard unforgiving surface all the time. <br /><br />I make no suggestions on fat. My opinion is that people can get enough saturated fat eating a “balanced” diet. Saturated fat is like sodium, easy to get enough even when trying to reduce it. I have a hunch that most who consume excessive amounts of saturated fat get it through processed foods, meats filled with fillers, meats from animals pumped to the max with hormones and feed nasty diets, junk food loaded with simple sugars and so on. Many who limit saturated fat choose a lunch consisting of a diet soda, a “light” yogurt, and a frozen “diet” meal. Just eat the fast food meal please. As far as the healthy fats go, I say grab them from a variety of sources. If you can buy at least some organic, get the things you consume the outsides of, berries for example. <br /><br />It will be impossible to determine by reducing eggs a bit with all other experimentation going on if the methionine content played a role in your anti-aging plan. <br /><br />I’m skeptical of wonder supplements. I stick to vitamins and minerals for supplementation. If a substance has promise I try to consume things that contain it. Who knows if it’s the substance itself or the collaborative group of chemicals found in the source? <br /><br />I think a health regimen should include many other things; sleep, hygiene (using toxic/processed cosmetics is really no different than eating processed food. Also flossing and dental care has tremendous benefits.), skin care (should one filter out chlorine content and other metals/garbage in shower water), eye care, relaxation/spiritual/social strategies, sex, and the list goes on. One could be doing the things in your health regimen and still be missing out on the practices just mentioned that could also add years. Good blog. ANONAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-35065758026260243392010-08-09T13:31:17.513+03:002010-08-09T13:31:17.513+03:00@ANON,
Thank you for your thoughtful comments. I ...@ANON,<br /><br />Thank you for your thoughtful comments. I certainly admit that "the more you think you know, the less you really know" is true to a degree; I've been proven wrong more times than I can remember. Still, there are two kinds of people in this world: those who don't even want to try to understand and those who do try. I prefer the latter group myself.<br /><br />As for alcohol, I used to think it was bad for health but chose to enjoy it nonetheless. It's only recently that I've read some positive things about alcohol (and not just red wine), so obviously I was interested.<br /><br />Yes, my exercise routine could be much better. I've pretty much switched from jogging to going to the gym. Although cardiovascular exercise may be a net positive, I'm skeptical of running these days. There's a good post on marathon runners over at the paleonu.com blog. I think strength training is the best way to go. And yes, I may be biased here because I enjoy the gym much more than I do running.<br /><br />There is of course always the chance that I will do an 180 degree on my current, somewhat negative stance on polyunsaturated fats, but I'm not sure what you are suggesting as an alternative. Should bloggers stick to their opinions, no matter what the science says? I don't consider myself as an expert, all I'm doing is presenting the results of the studies in what I hope to be an understandable manner, experiment on myself and try to form some kind of an overview of the whole thing. I do consider it learning, even if it is through trial and error.<br /><br />You make a good point about methionine. In the grand scheme of things, the difference it makes is probably very small. But that small difference is still interesting to me, and it looks like there are other people who are interested in it as well. If you want to play it safe, eat a "balanced" diet and get some exercise. It'll be better than the average diet for sure. But personally, I'm not into "slightly better than average", I'm into finding the optimal diet and *then* deciding which things I actually want to implement in my own diet. <br /><br />There's a lot of debate whether taking things like resveratrol makes sense at this point, because we don't know everything there is to know about them. But the fact is that we will never know *everything* about them. Everyone has to evaluate the risk/benefit ratio for themselves. There are many people who avoid more experimental supplements because there is no clear evidence that they increase lifespan, for example. They think it's an unnecessary gamble. But on the other hand, not doing anything and just waiting is a gamble too. It's just a different kind of risk.<br /><br />If the kind of advice you're looking for is "go for a jog and don't eat too much sugar", then there are a billion general heatlh blogs for that already. I do post about more broad health topics such as low-carb diets as well, but as you've noticed, a lot of this blog is about tweaking small things that might increase one's chances of making to longevity escape velocity. I find the tweaking fascinating, and there's not a whole lot of health blogs that deal with this aspect.<br /><br />Finally, there is indeed a chance that supplementing shortens your (or in this case my) life. I think that risk can be minimized through reading as much as possible on the subject, however. I wouldn't call myself an aggressive supplementer either -- in fact, the more I read, the more skeptical I am about most supplements, at least from a life extension perspective. The consider things I experiment to have a low risk and potentially high benefits (cognitive enhancers like ALCAR, for example).<br /><br />I'm glad you've found the blog entertaining (and even informative at times). Thanks again for the lengthy comment, always nice to read them. <br /><br />Take care and hope to see you on the blog,<br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-56669935824850600682010-08-04T20:09:45.765+03:002010-08-04T20:09:45.765+03:00I would like to say your posts are interesting and...I would like to say your posts are interesting and I have enjoyed your blog. I agree with your strategy of avoiding harmful things first, especially since many of them can be identified by anyone who stayed awake during junior high health. Things such as smoking and avoiding processed foods should be commonly avoided and the list goes on as far as obvious health risks are concerned. There are other strategies that should be part of a health regimen also such as brushing and flossing one’s teeth daily. The entertainment and amusing issues with your blog are with your experiments which seem to be custom fit to your viewpoints and reactionary based on studies. Your experimentation seems to suffer from the “more you think you know, the less you really know” syndrome. From what I have read it seems you enjoy alcohol consumption quite a bit so of course there are potential supporting studies relating to the health benefits of drinking beer and wine. I get the impression you could be exercising more often then you post, which I believe you admit. I personally would stress the importance of physical exercise and how your lack of it can be a major factor in your overall anti-aging strategy. I can’t imagine you would have a hard time posting studies suggesting that if one gets cardiovascular exercise a few times a week along with some moderate weight training that overall body health, aging, prevention of disease, etc would be dramatically lower. I’m not talking about turning into a gym rat or training for the Olympics. The suggestion is to get regular realistic cardiovascular and strength training. Going for a walk/run every once in a while (once a week) is like an obsessive exerciser who normally eats fast food but throws in a vegetable every once in a while. What’s the point? Also, perhaps in version 3.0 we readers will get some insight into your sleep habits and the importance (or lack of) of sleep in your health regimen.<br /> <br />I find the posts amusing when going on about highly scientific processes as a result of chemical reactions from fruits, vegetables, meats, and so on and their effect on the body only to realize that when another study comes out it’s time to do a 180 degree change. But hey that’s part of what an experiment and the “learning” process is I suppose. I particularly enjoy the comments about eggs and one poster’s reply that sea lion meat may be a reasonable substitute because some dude online posted a study touting its benefits. Rather than worry about eggs, consume a few in moderation and go for a jog in the morning. You’re only setting yourself up for heartbreak when you realize the methionine content makes no difference. There are many other examples of this which part of me thinks are silly but another part enjoys for both the humor and for the effort someone is putting into it. Would one really jeopardize their immortality efforts if they ate a reasonable spectrum of raw quality nuts in moderation rather than worrying about omega-3/omega-6 ratios? I’m not talking peanuts here but, maybe a few almonds, walnuts, etc. Perhaps the micronutrients found in these nuts will outweigh the “health risks” of the poor ratio.<br /> <br />I believe that as new information comes out we should take advantage of it. However, for many readers of your blog to follow your lead would be ridiculous. Wouldn’t be something if all the misc cocktails and herbal formulas used in aggressive experimenting were actually shortening your life! When I live longer than you, I’ll write about it! Thanks for being a guinea pig and providing me with entertainment and some information I have found useful. I’d love to see the health stats and physical condition of some of the posters who reply to your blog. Sincerely, ANONAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-67812935395674621112010-07-28T10:02:13.077+03:002010-07-28T10:02:13.077+03:00I should rephrase that: I doubt low-to-moderate al...I should rephrase that: I doubt low-to-moderate alcohol consumption has a big effect on vitamin D levels. Excess consumption may be a different matter.JLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-52861081648873910352010-07-28T09:59:15.027+03:002010-07-28T09:59:15.027+03:00@Blackhawk,
I doubt alcohol has a big effect on v...@Blackhawk,<br /><br />I doubt alcohol has a big effect on vitamin D status, but I could be wrong. Earlier it was thought that alcohol might in fact interfere with vitamin D production, resulting in lower levels. A new study suggests it does not:<br /><br />http://www.sciencedaily.com/releases/2010/04/100427131355.htm<br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-47510704113682466172010-07-27T20:43:35.344+03:002010-07-27T20:43:35.344+03:00Hi JLL,
Regarding research regarding alcohol, or a...Hi JLL,<br />Regarding research regarding alcohol, or anything else, the first thing that comes to my mind is: These results are very interesting, but..., is the study controlled for vitamin D? If not, I take the study's results to be dubious. I hope I live long enough to see the results from the grassrootshealth study. Although it is not properly controlled, it is a stab in the right direction. <br /><br />It is not surprising that eating dark grapes increases health, even though the grapes have a lot of fructose, a metabolic poison. The same is true for red wine and alcohol. It will be interesting to see exactly how pure ethanol provides its health benefit. Perhaps it spares vitamin D. <br /><br />Hope you find the vids interesting. I did.<br /><br />Sincerely, BlackhawkBlackhawknoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-48174484451334412352010-07-22T19:47:00.652+03:002010-07-22T19:47:00.652+03:00@Blackhawk,
Thanks for the videos, I'll check...@Blackhawk,<br /><br />Thanks for the videos, I'll check them out. <br /><br />Alcohol is indeed a poison, but then again, many things that are beneficial are, in fact, poisons. A good example are vegetables -- evolutionarily speaking, they don't "want" to be eaten, so they develop toxins as defense mechanisms (contrast this with fruit, which relies on getting eaten as a way to spread). Humans and vegetables have been in a sort of combat for hundreds of thousands of years. And yet we eat them with good appetite, and even consider them healthy.<br /><br />Even alcohol has its benefits. We're constantly told that a glass of red wine is good for you, but that's not what the longevity data says -- for Caucasian men, the *positive* effect on lifespan is still there even at much higher doses. And the real kicker is that it's not just red wine, it's beer, strong liquor, pure ethanol, whatever. I've been planning on doing a post on alcohol and longevity for a while now, so more on that later.<br /><br />So, at the moment, the overall benefit of moderate amounts of alcohol seems to me to outweigh the negatives, including any possible accelerated aging (which I doubt is the case in vivo, but I will read up on it).<br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-88628051545975025962010-07-22T19:17:54.383+03:002010-07-22T19:17:54.383+03:00Hi JLL.
Two vids on Youtube which have a lot to s...Hi JLL.<br /><br />Two vids on Youtube which have a lot to say on living longer (and healthier, of course) are: 1) SIRA: Origins Aging Cancer Diseases : http://www.youtube.com/watch?v=caLT_8MQZGw , and: 2) Sugar: The Bitter Truth : http://www.youtube.com/watch?v=dBnniua6-oM . The first vid discusses mitochondria and aging. The second vid discusses the metabolic poisons fructose and alcohol. I home-brew my own beer, so I was not pleased to learn how alcohol contributes to premature aging. <br /><br />Sincerely, BlackhawkBlackhawknoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-26102937932909030082010-06-01T19:19:46.720+03:002010-06-01T19:19:46.720+03:00@Mitch Fletcher,
I would take carnosine if I coul...@Mitch Fletcher,<br /><br />I would take carnosine if I could afford it :) it looks like a useful supplement overall.<br /><br />@Ork,<br /><br />Yes, I try to get most of the stuff from food -- not necessarily because I think it's somehow a superior way, but because I can't afford to supplement everything. In some cases the food matrix thing probably applies, but there are also cases where taking an extract or a single micronutrient is more efficient than eating the food (lutein is one example). I would judge on a case by case basis.<br /><br />@Anonymous,<br /><br />Well, I don't really care what "almost all academics" think or don't think (besides, given the latest reviews on yerba mate I would even disagree that most of them agree it's the temperature). By all means, drink yerba mate if it pleases you :) I am, for the time being, somewhat more cautious myself, however.<br /><br />- JLLJLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-45873995148702221492010-05-31T03:47:05.785+03:002010-05-31T03:47:05.785+03:00@ JLL
Fair points indeed. It would seem that ther...@ JLL<br /><br />Fair points indeed. It would seem that there isn't much evidence to suggest IF per se extends life, as per your most recent post.<br /><br />I think I will start taking carnosine, as being vegetarian I lack it in the diet and it may help with AGE prevention. I'm guessing you probably consider your dietary intake sufficient?<br /><br />@ Ork<br /><br />Yes I'm speculating, is that not ok? You sound a bit angry about something.<br />I don't believe sleep as a factor in longevity has been specifically mentioned in other posts, but that's fine, we're mainly discussing things at the cellular and molecular levels, so I don't expect that. I merely said I thought it was unfortunate that it is important for health (on a par with exercise) because I don't get enough by half. That was no reflection on anything else. Don't stress so much, Ork, you'll age faster. Relax :)Mitch Fletcherhttps://www.blogger.com/profile/05495559557084014273noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-35146239510210284422010-05-28T22:16:18.308+03:002010-05-28T22:16:18.308+03:00On Yerba Mate -- almost all academics that study Y...On Yerba Mate -- almost all academics that study Yerba Mate believe that the reason it causes cancer (of the throat - the cancer it usually causes) is because *of the extremely high temperatures that it's almost always drunk at* by the people of Argentina and Paraguay, where it is most common. If you drink it at warm but not scolding hot temperatures the way they do here (greetings from Argentina!) the cancer risk is eliminated.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-46080021798636053852010-05-27T01:01:43.703+03:002010-05-27T01:01:43.703+03:00I'd also like to add that I would not agree wi...I'd also like to add that I would not agree with the inclusion of flax/lignans.<br />"Food groups with decreasing levels of total phytoestrogens per 100 g are nuts and oilseeds, soy products, ..." PMID 16898863.<br /><br />I realize lignans have antioxidant properties, which I assume is the reason for their inclusion, but the risks to the HPTA outweigh the benefits to me (PMID 12727319). Unless lignans are more effective than other antioxidants, why take the risk?<br /><br />From what I've read, it is only the amino acid methionine that poses a possible danger, not protein in general. Looking forward to the posts on methionine.<br /><br />Do you try to get nutrition most of your nutrition from food itself? I try get what you've listed (except D3) from food if possible.Orkhttp://www.marksdailyapple.com/noreply@blogger.comtag:blogger.com,1999:blog-7049415900026167371.post-137311629594464112010-05-26T11:33:58.510+03:002010-05-26T11:33:58.510+03:00@Ork,
No, I definitely am not certain that dietar...@Ork,<br /><br />No, I definitely am not certain that dietary AGEs are to fear. What we do know is that when high-AGE diets are fed to diabetic rats, they do poorly. We also know that AGEs accumulate with aging in humans. The rest is largely speculation.<br /><br />I'm not very worried about dietary AGEs, really -- I'm more worried about endogenous AGEs, and I'm even more worried about ALEs (endogenous and exogenous; I don't know which ones are worse).JLLhttps://www.blogger.com/profile/01200324973565346888noreply@blogger.com